Exosome-coated metal-organic framework nanoparticles: An efficient drug delivery platform

Bernhard Illes; Patrick Hirschle; Sabine Barnert; Valentina Cauda; Stefan Wuttke; Hanna Engelke

doi:10.1021/acs.chemmater.7b02358

Exosome-coated metal-organic framework nanoparticles: An efficient drug delivery platform

Bernhard Illes
, Patrick Hirschle
, Sabine Barnert
, Valentina Cauda
, Stefan Wuttke
, Hanna Engelke

Research output: Contribution to journal › Article › peer-review

198 Citations (Scopus)

Abstract

Exosomes might provide additional important advantages as compared to artificial lipid layers as a capping system. They are endogenous liposomes present in many body liquids. They supposedly are nonimmunogenic and are used by cells for communication purposes. They combine the advantages of a lipid bilayer with a potential shielding from the immune system and, unlike artificial lipid bilayers, they have a not yet understood endogenous mechanism that supports release from the endosomal entrapment.

Original language	English
Pages (from-to)	8042-8046
Number of pages	5
Journal	Chemistry of Materials
Volume	29
Issue number	19
DOIs	https://doi.org/10.1021/acs.chemmater.7b02358
Publication status	Published - Oct 10 2017
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering
Materials Chemistry

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10.1021/acs.chemmater.7b02358

Cite this

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AU - Hirschle, Patrick

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AU - Cauda, Valentina

AU - Wuttke, Stefan

AU - Engelke, Hanna

PY - 2017/10/10

Y1 - 2017/10/10

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AB - Exosomes might provide additional important advantages as compared to artificial lipid layers as a capping system. They are endogenous liposomes present in many body liquids. They supposedly are nonimmunogenic and are used by cells for communication purposes. They combine the advantages of a lipid bilayer with a potential shielding from the immune system and, unlike artificial lipid bilayers, they have a not yet understood endogenous mechanism that supports release from the endosomal entrapment.

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M3 - Article

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Exosome-coated metal-organic framework nanoparticles: An efficient drug delivery platform

Abstract

ASJC Scopus subject areas

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