Expert-Group Practical Advice on Insulin Initiation and Titration for Patients with Type 2 Diabetes in the Gulf Region

Mohammed Hassanein; Walid Al Dahi; Husain Taha Radhi; Abdulraouf Aimahfouz; Juma Al Kaabi; Abdulmuhsen Alshammari; Abdullah Alfutaisi; Mussa H. Almalki; Rayaz Malik

doi:10.1159/000521437

Expert-Group Practical Advice on Insulin Initiation and Titration for Patients with Type 2 Diabetes in the Gulf Region

Mohammed Hassanein, Walid Al Dahi, Husain Taha Radhi, Abdulraouf Aimahfouz, Juma Al Kaabi, Abdulmuhsen Alshammari, Abdullah Alfutaisi, Mussa H. Almalki, Rayaz Malik

Research output: Contribution to journal › Review article › peer-review

Abstract

The type 2 diabetes mellitus (T2DM) management represents a major challenge in the Gulf region. Hyperglycemia is a major risk factor for microvascular and macrovascular complications and increased mortality. Early dietary and lifestyle changes alongside a step-wise targeted pharmacological approach to achieve a glycated hemoglobin (HbA_1c) level of <7% are recommended to limit these complications. However, achievement of this HbA_1c target remains a major challenge, especially in the Gulf region. Both physician and patient- led barriers limit timely initiation and titration of insulin. An expert-group advisory committee reviewed the current guideline recommendations, strategized best practice, and curated clinical practical advices to enable primarycare physicians to optimally initiate and titrate insulin in patients with T2DM.

Original language	English
Pages (from-to)	45-55
Number of pages	11
Journal	Dubai Diabetes and Endocrinology
Volume	28
Issue number	2
DOIs	https://doi.org/10.1159/000521437
Publication status	Published - Mar 17 2022
Externally published	Yes

Keywords

Glycated hemoglobin target
Glycemic control
Gulf countries
Insulin inertia
Insulin initiation
Primary-care centers
Primary-care physicians
Titration
Type 2 diabetes mellitus

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000521437

Cite this

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title = "Expert-Group Practical Advice on Insulin Initiation and Titration for Patients with Type 2 Diabetes in the Gulf Region",

abstract = "The type 2 diabetes mellitus (T2DM) management represents a major challenge in the Gulf region. Hyperglycemia is a major risk factor for microvascular and macrovascular complications and increased mortality. Early dietary and lifestyle changes alongside a step-wise targeted pharmacological approach to achieve a glycated hemoglobin (HbA1c) level of <7\% are recommended to limit these complications. However, achievement of this HbA1c target remains a major challenge, especially in the Gulf region. Both physician and patient- led barriers limit timely initiation and titration of insulin. An expert-group advisory committee reviewed the current guideline recommendations, strategized best practice, and curated clinical practical advices to enable primarycare physicians to optimally initiate and titrate insulin in patients with T2DM.",

keywords = "Glycated hemoglobin target, Glycemic control, Gulf countries, Insulin inertia, Insulin initiation, Primary-care centers, Primary-care physicians, Titration, Type 2 diabetes mellitus",

author = "Mohammed Hassanein and \{Al Dahi\}, Walid and Radhi, \{Husain Taha\} and Abdulraouf Aimahfouz and \{Al Kaabi\}, Juma and Abdulmuhsen Alshammari and Abdullah Alfutaisi and Almalki, \{Mussa H.\} and Rayaz Malik",

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year = "2022",

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doi = "10.1159/000521437",

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AU - Hassanein, Mohammed

AU - Al Dahi, Walid

AU - Radhi, Husain Taha

AU - Aimahfouz, Abdulraouf

AU - Al Kaabi, Juma

AU - Alshammari, Abdulmuhsen

AU - Alfutaisi, Abdullah

AU - Almalki, Mussa H.

AU - Malik, Rayaz

PY - 2022/3/17

Y1 - 2022/3/17

N2 - The type 2 diabetes mellitus (T2DM) management represents a major challenge in the Gulf region. Hyperglycemia is a major risk factor for microvascular and macrovascular complications and increased mortality. Early dietary and lifestyle changes alongside a step-wise targeted pharmacological approach to achieve a glycated hemoglobin (HbA1c) level of <7% are recommended to limit these complications. However, achievement of this HbA1c target remains a major challenge, especially in the Gulf region. Both physician and patient- led barriers limit timely initiation and titration of insulin. An expert-group advisory committee reviewed the current guideline recommendations, strategized best practice, and curated clinical practical advices to enable primarycare physicians to optimally initiate and titrate insulin in patients with T2DM.

AB - The type 2 diabetes mellitus (T2DM) management represents a major challenge in the Gulf region. Hyperglycemia is a major risk factor for microvascular and macrovascular complications and increased mortality. Early dietary and lifestyle changes alongside a step-wise targeted pharmacological approach to achieve a glycated hemoglobin (HbA1c) level of <7% are recommended to limit these complications. However, achievement of this HbA1c target remains a major challenge, especially in the Gulf region. Both physician and patient- led barriers limit timely initiation and titration of insulin. An expert-group advisory committee reviewed the current guideline recommendations, strategized best practice, and curated clinical practical advices to enable primarycare physicians to optimally initiate and titrate insulin in patients with T2DM.

KW - Glycated hemoglobin target

KW - Glycemic control

KW - Gulf countries

KW - Insulin inertia

KW - Insulin initiation

KW - Primary-care centers

KW - Primary-care physicians

KW - Titration

KW - Type 2 diabetes mellitus

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DO - 10.1159/000521437

M3 - Review article

AN - SCOPUS:85198006736

SN - 2673-1797

VL - 28

SP - 45

EP - 55

JO - Dubai Diabetes and Endocrinology

JF - Dubai Diabetes and Endocrinology

IS - 2

ER -

Expert-Group Practical Advice on Insulin Initiation and Titration for Patients with Type 2 Diabetes in the Gulf Region

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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