Explainable Artificial Intelligence in Medical Diagnostics: Insights into Alzheimer’s Disease

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Alzheimer’s Disease (AD) is the most prevalent form of dementia globally, which presents a pressing health issue, especially in aging populations. Its early detection is critical to initiating appropriate care and therapeutic strategies. However, AD’s complex and multifaceted nature poses considerable challenges to accurate and early diagnosis. Machine learning (ML) models have emerged as promising disease detection and diagnosis tools, including AD. However, despite their superior predictive performance, these models are often viewed as “black boxes” due to their complex internal workings, which are not readily interpretable. This study aims to explore the application of Explainable Artificial Intelligence (XAI) techniques to enhance the interpretability of the best-performing ML classifier for AD detection. The robust analysis offers significant insights into the ML model’s decision-making processes, thereby enhancing their interpretability and bolstering confidence in their use for early AD detection.

Original languageEnglish
Title of host publicationMachine Learning and Principles and Practice of Knowledge Discovery in Databases - International Workshops of ECML PKDD 2023, Revised Selected Papers
EditorsRosa Meo, Fabrizio Silvestri
PublisherSpringer Science and Business Media Deutschland GmbH
Pages312-319
Number of pages8
ISBN (Print)9783031746390
DOIs
Publication statusPublished - 2025
EventJoint European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases, ECML PKDD 2023 - Turin, Italy
Duration: Sept 18 2023Sept 22 2023

Publication series

NameCommunications in Computer and Information Science
Volume2136 CCIS
ISSN (Print)1865-0929
ISSN (Electronic)1865-0937

Conference

ConferenceJoint European Conference on Machine Learning and Principles and Practice of Knowledge Discovery in Databases, ECML PKDD 2023
Country/TerritoryItaly
CityTurin
Period9/18/239/22/23

Keywords

  • Aging Problem
  • Alzheimer Disease
  • Explainable Artificial Intelligence
  • Machine learning

ASJC Scopus subject areas

  • General Computer Science
  • General Mathematics

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