Exploring the antioxidant potential of medicinal plants in the United Arab Emirates (UAE): Emphasizing their significance in novel drug development

Khalfan Al Naqbi, Ramya Manoharan, Chythra Somanathan Nair, Karthishwaran Kandhan, Mohammed Salem Alyafei, Abdul Jaleel

Research output: Contribution to journalReview articlepeer-review

Abstract

Recent scientific investigations across the globe have unveiled the medicinal attributes of plants, subject to scrutiny due to their effective pharmacological properties, economic feasibility, and less toxicity. Compounds such as polyphenols demonstrate the ability to scavenge free radicals and enhance a balance between oxidative stress and antioxidant property. The mode of action of antioxidants involves suppressing the formation of reactive oxygen species either through enzyme inhibition or by chelating trace elements. Antioxidant assays such as DPPH, FRAP, ABTS have been used to evaluate the scavenging effect of antioxidants. Natural antioxidants from plants play a crucial role in human health and are beneficial in combating various diseases like cardiovascular disorders, lung damage, and inflammation. Native plants in the United Arab Emirates (UAE) have served as a valuable resource in traditional medicine. However, there are still gaps in understanding and research regarding the phytochemical and pharmacological aspects of these plants. This review aims to explore the researches in medicinal plants in the UAE as a potential source of antioxidants, highlighting their value for the development of new drugs.

Original languageEnglish
Article number3113
JournalPharmacy Practice
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 1 2025

Keywords

  • antioxidant
  • drug development
  • free radical scavenger
  • immune booster
  • plant extracts

ASJC Scopus subject areas

  • Pharmacy
  • Pharmaceutical Science

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