Expression of HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris

Amr M. Sarwat; Suhail Al-Salam

doi:10.1007/s11060-008-9729-8

Expression of HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris

Amr M. Sarwat
, Suhail Al-Salam

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Schwannomatosis is a clinical syndrome that requires thorough clinical and radiological assessments before the diagnosis is made. Although schwannomatosis has been reported before, all were in multiple organ sites. The authors report a case of multiple intra-dural schwannomas of the conus medullaris expressing HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein; which to the best of our knowledge has not been previously reported in schwanomatosis.

Original language	English
Pages (from-to)	111-115
Number of pages	5
Journal	Journal of Neuro-Oncology
Volume	92
Issue number	1
DOIs	https://doi.org/10.1007/s11060-008-9729-8
Publication status	Published - 2009

Keywords

Cox-2
Galectin-3
HIF-1
Schwannomatosis
Spinal cord
WT-1

ASJC Scopus subject areas

Oncology
Neurology
Clinical Neurology
Cancer Research

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abstract = "Schwannomatosis is a clinical syndrome that requires thorough clinical and radiological assessments before the diagnosis is made. Although schwannomatosis has been reported before, all were in multiple organ sites. The authors report a case of multiple intra-dural schwannomas of the conus medullaris expressing HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein; which to the best of our knowledge has not been previously reported in schwanomatosis.",

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AU - Sarwat, Amr M.

AU - Al-Salam, Suhail

PY - 2009

Y1 - 2009

N2 - Schwannomatosis is a clinical syndrome that requires thorough clinical and radiological assessments before the diagnosis is made. Although schwannomatosis has been reported before, all were in multiple organ sites. The authors report a case of multiple intra-dural schwannomas of the conus medullaris expressing HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein; which to the best of our knowledge has not been previously reported in schwanomatosis.

AB - Schwannomatosis is a clinical syndrome that requires thorough clinical and radiological assessments before the diagnosis is made. Although schwannomatosis has been reported before, all were in multiple organ sites. The authors report a case of multiple intra-dural schwannomas of the conus medullaris expressing HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein; which to the best of our knowledge has not been previously reported in schwanomatosis.

KW - Cox-2

KW - Galectin-3

KW - HIF-1

KW - Schwannomatosis

KW - Spinal cord

KW - WT-1

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IS - 1

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Expression of HIF-1, galectin-3, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris

Abstract

Keywords

ASJC Scopus subject areas

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