First-Principles Modeling for DNA Bases via Monolayer MoS2Sensor with a Nanopore

Asma Wasfi; Mohamed Atef; Falah Awwad

doi:10.1109/ICM52667.2021.9664928

First-Principles Modeling for DNA Bases via Monolayer MoS₂Sensor with a Nanopore

Asma Wasfi, Mohamed Atef, Falah Awwad

Department of Electrical and Communication Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

Lately, molybdenum disulfide (MoS2) has drawn massive interest in the biomolecular detection field due to its notable optoelectronic characteristics and its wide surface area. Here, we study a novel monolayer MoS2 sensor with gold electrodes where a nanopore is placed in the middle of the MoS2 sheet which enables quick, selective, and sensitive DNA nucleobase detection. The MoS2 sensor exhibits distinguishable electronic properties for the different DNA nucleobases (Cytosine, Adenine, Thymine, and Guanine). Non-equilibrium Green's function integrated with density functional theory is utilized to inspect the detection mechanism. This research can promote a novel sensing platform utilizing MoS2.

Original language	English
Title of host publication	2021 International Conference on Microelectronics, ICM 2021
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	220-223
Number of pages	4
ISBN (Electronic)	9781665408394
DOIs	https://doi.org/10.1109/ICM52667.2021.9664928
Publication status	Published - 2021
Event	2021 International Conference on Microelectronics, ICM 2021 - New Cairo City, Egypt Duration: Dec 19 2021 → Dec 22 2021

Publication series

Name	Proceedings of the International Conference on Microelectronics, ICM

Conference

Conference	2021 International Conference on Microelectronics, ICM 2021
Country/Territory	Egypt
City	New Cairo City
Period	12/19/21 → 12/22/21

Keywords

DNA sequencing
Molybdenum disulfide (MoS)
density functional theory
electronic properties
nanopore

ASJC Scopus subject areas

Electrical and Electronic Engineering

Access to Document

10.1109/ICM52667.2021.9664928

Cite this

Wasfi, A., Atef, M., & Awwad, F. (2021). First-Principles Modeling for DNA Bases via Monolayer MoS₂Sensor with a Nanopore. In 2021 International Conference on Microelectronics, ICM 2021 (pp. 220-223). (Proceedings of the International Conference on Microelectronics, ICM). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICM52667.2021.9664928

First-Principles Modeling for DNA Bases via Monolayer MoS₂Sensor with a Nanopore. / Wasfi, Asma; Atef, Mohamed ; Awwad, Falah.
2021 International Conference on Microelectronics, ICM 2021. Institute of Electrical and Electronics Engineers Inc., 2021. p. 220-223 (Proceedings of the International Conference on Microelectronics, ICM).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Wasfi, A, Atef, M & Awwad, F 2021, First-Principles Modeling for DNA Bases via Monolayer MoS₂Sensor with a Nanopore. in 2021 International Conference on Microelectronics, ICM 2021. Proceedings of the International Conference on Microelectronics, ICM, Institute of Electrical and Electronics Engineers Inc., pp. 220-223, 2021 International Conference on Microelectronics, ICM 2021, New Cairo City, Egypt, 12/19/21. https://doi.org/10.1109/ICM52667.2021.9664928

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