TY - GEN
T1 - First-Principles Modeling for DNA Bases via Z-shaped Graphene Nanoribbon with a Nanogap
AU - Wasfi, Asma
AU - Awwad, Falah
N1 - Funding Information:
*Research supported by United Arab Emirates University with Fund number 31R128.
Funding Information:
ACKNOWLEDGMENT The authors would like to acknowledge the financial support by United Arab Emirates University (Zayed Center for Health Sciences) with Fund number 31R128.
Publisher Copyright:
© 2019 IEEE.
PY - 2019/10
Y1 - 2019/10
N2 - DNA sequencing is a significant technique to detect genetic illnesses and various diseases. Quick, accurate, and low cost DNA sequencing approach would revolutionize medicine. In this paper, a two-terminal z-shaped sensor with a nanogap is designed and studied to detect the DNA sequence. The z-shaped sensor is made of two metallic zigzag graphene nanoribbon (ZGNR), a semiconducting channel made of armchair graphene nanoribbon (AGNR), and a nanogap in the middle of the channel whose edge carbon atoms are passivated by either hydrogen or nitrogen. Placing a DNA base into the nanogap impacts the charge density of the sensor leading to unique signature for each of the four DNA bases. The z-shaped sensor performance was studied by non-equilibrium Green's function combined with density functional theory (NEGF+DFT). The transverse current and the transmission spectrum of the DNA bases within the nanogap are investigated with variation in the base orientation. The proposed sensor is highly useful for real application of quick, low-cost, and accurate DNA detection.
AB - DNA sequencing is a significant technique to detect genetic illnesses and various diseases. Quick, accurate, and low cost DNA sequencing approach would revolutionize medicine. In this paper, a two-terminal z-shaped sensor with a nanogap is designed and studied to detect the DNA sequence. The z-shaped sensor is made of two metallic zigzag graphene nanoribbon (ZGNR), a semiconducting channel made of armchair graphene nanoribbon (AGNR), and a nanogap in the middle of the channel whose edge carbon atoms are passivated by either hydrogen or nitrogen. Placing a DNA base into the nanogap impacts the charge density of the sensor leading to unique signature for each of the four DNA bases. The z-shaped sensor performance was studied by non-equilibrium Green's function combined with density functional theory (NEGF+DFT). The transverse current and the transmission spectrum of the DNA bases within the nanogap are investigated with variation in the base orientation. The proposed sensor is highly useful for real application of quick, low-cost, and accurate DNA detection.
KW - DNA sequencing
KW - density functional theory
KW - electronic transport
KW - graphene nanoribbon
KW - nanogap
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U2 - 10.1109/SENSORS43011.2019.8956659
DO - 10.1109/SENSORS43011.2019.8956659
M3 - Conference contribution
AN - SCOPUS:85078704276
T3 - Proceedings of IEEE Sensors
BT - 2019 IEEE Sensors, SENSORS 2019 - Conference Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 18th IEEE Sensors, SENSORS 2019
Y2 - 27 October 2019 through 30 October 2019
ER -