TY - JOUR
T1 - Fish on metaphase and interphase chromosomes demonstrates the physical order of the genes for GPI, CRC, and LIPE in pigs
AU - Chowdhary, Bhanu P.
AU - de la Sena, C.
AU - Harbitz, I.
AU - Eriksson, L.
AU - Gustavsson, I.
PY - 1995
Y1 - 1995
N2 - The porcine genes for glucose phosphate isomerase (GPI), calcium release channel (CRC), and hormone-sensitive lipase (LIPE) map to the long arm of chromosome 6. Earlier studies, using fluorescence in situ hybridization (FISH), mapped the three loci to the same band, viz., 6q12. To ascertain the relative order of the three genes, we first conducted three double-color FISH experiments, cohybridizing two of the probes at a time. These experiments demonstrated that the gene order was cen-GPI-CRC-LIPE. This order was confirmed by cohybridizing the three probes to both metaphase and interphase chromosomes.
AB - The porcine genes for glucose phosphate isomerase (GPI), calcium release channel (CRC), and hormone-sensitive lipase (LIPE) map to the long arm of chromosome 6. Earlier studies, using fluorescence in situ hybridization (FISH), mapped the three loci to the same band, viz., 6q12. To ascertain the relative order of the three genes, we first conducted three double-color FISH experiments, cohybridizing two of the probes at a time. These experiments demonstrated that the gene order was cen-GPI-CRC-LIPE. This order was confirmed by cohybridizing the three probes to both metaphase and interphase chromosomes.
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U2 - 10.1159/000134101
DO - 10.1159/000134101
M3 - Article
C2 - 7656591
AN - SCOPUS:0029129101
SN - 0301-0171
VL - 71
SP - 175
EP - 178
JO - Cytogenetics and Cell Genetics
JF - Cytogenetics and Cell Genetics
IS - 2
ER -