Fitting the Hill Equation to Data: A Statistical Approach

N. J.D. Nagelkerke, J. Strackee

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


A procedure is presented for fitting the hyperbolic Hill equation to data. The procedure is a maximum likelihood method applied to a statistical specification of the problem which allows for measurement errors in two dimensions. The procedure is found to give an excellent fit. Problems encountered with the estimation of parameters when the estimates are highly correlated due to improper spacing of the observations are discussed.

Original languageEnglish
Pages (from-to)467-469
Number of pages3
JournalIEEE Transactions on Biomedical Engineering
Issue number6
Publication statusPublished - Jun 1982
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering


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