Forgotten topological index of chemical structure in drugs

Wei Gao, Muhammad Kamran Siddiqui, Muhammad Imran, Muhammad Kamran Jamil, Mohammad Reza Farahani

Research output: Contribution to journalArticlepeer-review

144 Citations (Scopus)

Abstract

A massive of early drug tests implies that there exist strong inner relationships between the bio-medical and pharmacology characteristics of drugs and their molecular structures. The forgotten topological index was defined to be used in the analysis of drug molecular structures, which is quite helpful for pharmaceutical and medical scientists to grasp the biological and chemical characteristics of new drugs. Such tricks are popularly employed in developing countries where enough money is lacked to afford the relevant chemical reagents and equipment. In our article, by means of drug molecular structure analysis and edge dividing technology, we present the forgotten topological index of several widely used chemical structures which often appear in drug molecular graphs.

Original languageEnglish
Pages (from-to)258-264
Number of pages7
JournalSaudi Pharmaceutical Journal
Volume24
Issue number3
DOIs
Publication statusPublished - May 1 2016
Externally publishedYes

Keywords

  • Benzenoid series
  • Bridge graph
  • Computational medical
  • Dendrimer stars
  • Forgotten topological index

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

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