From FHB Resistance QTLs to Candidate Genes Identification in Triticum aestivum L.

Mouna Choura, Moez Hanin, Ahmed Rebaï, Khaled Masmoudi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Fusarium head blight (FHB) caused by Fusarium graminearum is a worldwide destructive disease affecting cereals such as wheat. FHB resistance is a quantitative trait, and information for FHB resistance QTLs in wheat is available. However, little is known about genes underlying the FHB resistance QTL regions. Using a computational approach in this study, we have mined eight FHB resistance QTLs in wheat and predicted the candidate genes falling within these QTL intervals based on the available sequences and markers. A total of 18 genomic scaffolds located at chromosomes 2AL, 2DL, 3B and 4BS were prioritized to harbor FHB-resistant candidate genes. These genes are mainly involved in plant defense response, immune regulation and cellular detoxification. We believe that our results constitute a starting point for further validation to improve FHB-resistant bread wheat varieties.

Original languageEnglish
Pages (from-to)352-356
Number of pages5
JournalInterdisciplinary Sciences - Computational Life Sciences
Issue number4
Publication statusPublished - Dec 1 2016


  • Candidate gene
  • FHB resistance
  • QTL
  • Triticum aestivum

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • Computer Science Applications
  • Health Informatics


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