TY - JOUR
T1 - Gestational diabetes
T2 - Relevance of diagnostic criteria and preventive strategies for Type 2 diabetes mellitus
AU - Agarwal, Mukesh M.
AU - Dhatt, Gurdeep S.
AU - Zayed, Reem
AU - Bali, Namita
PY - 2007/9
Y1 - 2007/9
N2 - Objective: Women with gestational diabetes mellitus (GDM) are at risk to develop Type 2 diabetes mellitus (DM2). The aim of this study was to compare the effect of three international diagnostic criteria on the prevalence of GDM with its implications for prevention of DM2 in the population. Materials and methods: One thousand one hundred and seventy-two pregnant women, who underwent the 75-g oral glucose tolerance test for routine, antenatal GDM screening, were classified using the criteria of the American Diabetes Association (ADA), the World Health Organization (WHO) and Australasian Diabetes in Pregnancy Society (ADIPS). The population-attributable risk, (PAR) was used to estimate the proportion of women with DM2 in the community, who may have been identified much in advance for intervention, by a GDM pregnancy. Results: Using the ADA, WHO and ADPIS criteria, respectively: (a) the prevalence of GDM was 166 (14.2%), 242 (20.6%) and 271 (23.1%) (p < 0.0001); (b) The PAR (95% CI) was 42% (31-52%); 51% (39-62%) and 54% (42-64%). Overall, by all three criteria, 132 (11.3%) women had GDM while 859 (73.3%) were without GDM; the remaining 181 (15.4%) women had classification differences between them. Conclusion: The universal acceptance and the ability of the WHO criteria to detect over half the women with DM2 earlier during pregnancy, makes it ideally suited to identify women with GDM.
AB - Objective: Women with gestational diabetes mellitus (GDM) are at risk to develop Type 2 diabetes mellitus (DM2). The aim of this study was to compare the effect of three international diagnostic criteria on the prevalence of GDM with its implications for prevention of DM2 in the population. Materials and methods: One thousand one hundred and seventy-two pregnant women, who underwent the 75-g oral glucose tolerance test for routine, antenatal GDM screening, were classified using the criteria of the American Diabetes Association (ADA), the World Health Organization (WHO) and Australasian Diabetes in Pregnancy Society (ADIPS). The population-attributable risk, (PAR) was used to estimate the proportion of women with DM2 in the community, who may have been identified much in advance for intervention, by a GDM pregnancy. Results: Using the ADA, WHO and ADPIS criteria, respectively: (a) the prevalence of GDM was 166 (14.2%), 242 (20.6%) and 271 (23.1%) (p < 0.0001); (b) The PAR (95% CI) was 42% (31-52%); 51% (39-62%) and 54% (42-64%). Overall, by all three criteria, 132 (11.3%) women had GDM while 859 (73.3%) were without GDM; the remaining 181 (15.4%) women had classification differences between them. Conclusion: The universal acceptance and the ability of the WHO criteria to detect over half the women with DM2 earlier during pregnancy, makes it ideally suited to identify women with GDM.
KW - Diabetes mellitus prevention
KW - Diagnostic criteria
KW - Gestational diabetes
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U2 - 10.1007/s00404-007-0334-4
DO - 10.1007/s00404-007-0334-4
M3 - Article
C2 - 17318559
AN - SCOPUS:34547221498
SN - 0932-0067
VL - 276
SP - 237
EP - 243
JO - Archives of Gynecology and Obstetrics
JF - Archives of Gynecology and Obstetrics
IS - 3
ER -