Group A streptococcal throat colonization is a dynamic phenomenon

K. P. Dawson, H. Nsanze, A. S. Ameen, N. Mustafa

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


In order to gain knowledge about the nature of group A streptococcal throat colonization of asymptomatic children, we studied a cohort of healthy children selected at random. Those with throat cultures positive for group A Streptococci (GAS) were followed for 5 weeks. Repeat throat swabs were obtained at weekly intervals for antigen detection and culture. GAS obtained were serotyped for T antigen. Twenty-two children were identified as having GAS and 50% had a positive antigen test and culture at least five times in 6 weeks. There was no consistent pattern in the typeable organisms. Most individuals had more than one T-type alternating with non-T-typeable organisms. We conclude that colonization may be a dynamic process involving numerous organism serotypes, which wax and wane.

Original languageEnglish
Pages (from-to)16-21
Number of pages6
JournalAnnals of Tropical Paediatrics
Issue number1
Publication statusPublished - Mar 2000

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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