Heterogeneity of non-serotypable Campylobacter jejuni isolates

Ágnes Sonnevend, T. Pál

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Several phenotypic and genotypic methods are currently used to identify subtypes of Campylobacter jejuni isolates. Of the phenotypic methods one, i.e. serotyping based on the heat stable antigen, is often hindered by the relatively large number of un-typable (NT) strains. Little is known, however, about the heterogeneity of the group formed by these NT strains. Therefore we serotyped 92 Hungarian, non-outbreak C. jejuni isolates and subjected the 28 NT strains to molecular analysis using PCR-RFLP of the flaA gene and to pulsed-field gel electrophoresis. With both methods the NT strains were classified into several molecular types (17 and 25, respectively), while the number of subgroups based on the results of the two techniques combined was twenty-six. These results indicate that the NT group of strains is extremely heterogeneous in Hungary, and the epidemiological connection between two NT isolates cannot be established or excluded without the use of molecular typing techniques.

Original languageEnglish
Pages (from-to)171-181
Number of pages11
JournalActa Microbiologica et Immunologica Hungarica
Issue number2
Publication statusPublished - 2006
Externally publishedYes


  • Campylobacter jejuni subtypes
  • Molecular analysis

ASJC Scopus subject areas

  • General Immunology and Microbiology


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