High enzyme concentration model for the kinetics of hydrolysis of oils by lipase

Sulaiman Al-Zuhair, K. B. Ramachandran, Masitah Hasan

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


A mathematical model to predict the hydrolysis rate of oils by lipase, from a proposed kinetic mechanism of the reaction is derived. The model predicts interfacial saturation at high enzyme concentration. It is used to determine, under different operating conditions, the critical enzyme concentration, i.e., the enzyme concentration at which the interface between the oil and the aqueous phase containing the enzyme is saturated. To verify the model predictions, experimental results of the hydrolysis of palm oil and sunflower oil are used. The model predictions closely agree with the experimental results for sun flower oil. The sensitivity of the model predictions to the values of the kinetic parameters is also investigated.

Original languageEnglish
Pages (from-to)7-11
Number of pages5
JournalChemical Engineering Journal
Issue number1-3
Publication statusPublished - Oct 15 2004
Externally publishedYes


  • Interfacial saturation
  • Kinetic model
  • Lipase
  • Oil hydrolysis
  • Palm oil
  • Sunflower oil

ASJC Scopus subject areas

  • General Chemistry
  • Environmental Chemistry
  • General Chemical Engineering
  • Industrial and Manufacturing Engineering


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