Hormonal Therapies in the Management of Acne Vulgaris

Gaurav Dash, Anant Patil, George Kroumpouzos, Hassan Galadari, Michael H. Gold, Stephan Grabbe, Mohamad Goldust

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Acne vulgaris is a multifactorial chronic disorder of the pilosebaceous unit. Established treatments include topical retinoids, antibiotics in mild cases, and oral antibiotics and isotretinoin in moderate to severe cases. Anti-androgens and other hormonal therapies constitute another group of drugs in the armamentarium of acne management. These can be used in patients who do not respond to the aforementioned treatments or when other systemic drugs cannot be tolerated. Recent approval of topical androgen receptor blocker is an additional armamentarium for the management of acne. Considering limited systemic exposure and good efficacy, it has potential for wide usage in patients with acne. In this article, we critically review currently available hormonal treatment options based on published literature search of an electronic database (MEDLINE/PubMed) Do Not Copyperformed through June 2021.

Original languageEnglish
Pages (from-to)618-623
Number of pages6
JournalJournal of Drugs in Dermatology
Issue number6
Publication statusPublished - Jun 2022

ASJC Scopus subject areas

  • General Medicine


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