HPLC analysis and detection of L-deprenyl

V. Csomor, R. Laufer, Z. Pöstényi, H. Kalász, E. Adeghate, S. M. Nurulain, K. Tekes, A. Adem

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


L-Deprenyl and its major metabolites were subjected to reversed-phase highperformance liquid chromatography (HPLC). The separation was monitored using both ultraviolet (UV) and electrochemical detectors. Ultraviolet absorbance detected L-deprenyl, L-nordeprenyl, L-methamphetamine, and L-amphetamine. Amperometric detection was specific and sensitive to the parent compound (L-deprenyl, a tertiary amine) only. Peaks of the major L-deprenyl metabolites did not give any comparable signal using amperometric monitoring.

Original languageEnglish
Pages (from-to)649-656
Number of pages8
JournalActa Chromatographica
Issue number4
Publication statusPublished - Dec 1 2014


  • Amperometric detection
  • HPLC
  • L-deprenyl
  • Metabolites
  • UV detection

ASJC Scopus subject areas

  • General Chemistry


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