Hyperferritinemia in a woman with systemic lupus erythematosus, severe nephritis and an iron-rich intraspinal schwannoma mimicking lupus myelopathy

W. Conca, M. Al-Hakim, N. Moussa, S. Al-Salam, P. Corr

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

We describe a lupus flare in a 59-year-old woman who presented with pancytopenia, nephritis, severe renal dysfunction and marked hyperferritinemia. The course of the disease was further complicated by an iron-laden, intraspinal ancient schwannoma that compressed the cervical cord mimicking a lupus-related myelopathy and was removed surgically. Treatment with mycophenolate mofetil (MMF) and prednisone induced a gradual decline in levels of serum ferritin with a concomitant improvement in renal function and reduction of proteinuria. Serum ferritin may be a useful marker of the response to treatment with MMF in renal lupus.

Original languageEnglish
Pages (from-to)834-837
Number of pages4
JournalClinical and Experimental Rheumatology
Volume27
Issue number5
Publication statusPublished - 2009

Keywords

  • Ferritins
  • Lupus nephritis
  • Mycophenolate mofetil
  • Neurilemmoma
  • Spinal cord diseases

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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