Hypocholesterolaemic effect and anti-hypertensive properties of probiotics and prebiotics: A review

Fatemeh Miremadi; Frank Sherkat; Lily Stojanovska

doi:10.1016/j.jff.2016.06.016

Hypocholesterolaemic effect and anti-hypertensive properties of probiotics and prebiotics: A review

Fatemeh Miremadi, Frank Sherkat, Lily Stojanovska

Research output: Contribution to journal › Review article › peer-review

45 Citations (Scopus)

Abstract

Hypercholesterolaemia (HCE) and hypertension (HT) are two major contributing factors in development of cardiovascular disease (CVD). As synthetic medications used to treat HCE and HT can cause several side effects such as nausea, vomiting and abdominal pain, various dietary approaches have been proposed to improve the HCE and HT at the population level. Most popular dietary intervention includes the use of probiotics and prebiotics in the development of functional foods. This review covers (1) the hypocholesterolaemic effects and anti-hypertensive properties of probiotics and prebiotics via several mechanisms, (2) the evidence generated from both in vitro experiments and in vivo trials and some controversial findings that are raised, (3) the effective dosage of prebiotics and probiotics, and (4) safety issues regarding the use of probiotics and prebiotics in human diet.

Original language	English
Pages (from-to)	497-510
Number of pages	14
Journal	Journal of Functional Foods
Volume	25
DOIs	https://doi.org/10.1016/j.jff.2016.06.016
Publication status	Published - Aug 1 2016
Externally published	Yes

Keywords

Anti-hypertensive property
Hypercholesterolaemia
Hypertension
Hypocholesterolaemic effect
Synbiotic

ASJC Scopus subject areas

Food Science
Medicine (miscellaneous)
Nutrition and Dietetics

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10.1016/j.jff.2016.06.016

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title = "Hypocholesterolaemic effect and anti-hypertensive properties of probiotics and prebiotics: A review",

abstract = "Hypercholesterolaemia (HCE) and hypertension (HT) are two major contributing factors in development of cardiovascular disease (CVD). As synthetic medications used to treat HCE and HT can cause several side effects such as nausea, vomiting and abdominal pain, various dietary approaches have been proposed to improve the HCE and HT at the population level. Most popular dietary intervention includes the use of probiotics and prebiotics in the development of functional foods. This review covers (1) the hypocholesterolaemic effects and anti-hypertensive properties of probiotics and prebiotics via several mechanisms, (2) the evidence generated from both in vitro experiments and in vivo trials and some controversial findings that are raised, (3) the effective dosage of prebiotics and probiotics, and (4) safety issues regarding the use of probiotics and prebiotics in human diet.",

keywords = "Anti-hypertensive property, Hypercholesterolaemia, Hypertension, Hypocholesterolaemic effect, Synbiotic",

author = "Fatemeh Miremadi and Frank Sherkat and Lily Stojanovska",

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T2 - A review

AU - Miremadi, Fatemeh

AU - Sherkat, Frank

AU - Stojanovska, Lily

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Hypercholesterolaemia (HCE) and hypertension (HT) are two major contributing factors in development of cardiovascular disease (CVD). As synthetic medications used to treat HCE and HT can cause several side effects such as nausea, vomiting and abdominal pain, various dietary approaches have been proposed to improve the HCE and HT at the population level. Most popular dietary intervention includes the use of probiotics and prebiotics in the development of functional foods. This review covers (1) the hypocholesterolaemic effects and anti-hypertensive properties of probiotics and prebiotics via several mechanisms, (2) the evidence generated from both in vitro experiments and in vivo trials and some controversial findings that are raised, (3) the effective dosage of prebiotics and probiotics, and (4) safety issues regarding the use of probiotics and prebiotics in human diet.

AB - Hypercholesterolaemia (HCE) and hypertension (HT) are two major contributing factors in development of cardiovascular disease (CVD). As synthetic medications used to treat HCE and HT can cause several side effects such as nausea, vomiting and abdominal pain, various dietary approaches have been proposed to improve the HCE and HT at the population level. Most popular dietary intervention includes the use of probiotics and prebiotics in the development of functional foods. This review covers (1) the hypocholesterolaemic effects and anti-hypertensive properties of probiotics and prebiotics via several mechanisms, (2) the evidence generated from both in vitro experiments and in vivo trials and some controversial findings that are raised, (3) the effective dosage of prebiotics and probiotics, and (4) safety issues regarding the use of probiotics and prebiotics in human diet.

KW - Anti-hypertensive property

KW - Hypercholesterolaemia

KW - Hypertension

KW - Hypocholesterolaemic effect

KW - Synbiotic

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JO - Journal of Functional Foods

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ER -

Hypocholesterolaemic effect and anti-hypertensive properties of probiotics and prebiotics: A review

Abstract

Keywords

ASJC Scopus subject areas

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