Immobilization of enzymes in porous solids under restricted diffusion conditions

Md M. Hossain; D. D. Do; J. E. Bailey

doi:10.1002/aic.690320705

Immobilization of enzymes in porous solids under restricted diffusion conditions

Md M. Hossain, D. D. Do, J. E. Bailey

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

A restricted diffusion model is developed to study the immobilization of enzyme in porous solid supports. Simulation studies have been carried out for various combinations of process variables and parameters of the immobilization system. The model has also been used to develop a method for estimating the intrinsic rate constant of immobilization when enzyme diffusion into the support is restricted. Results of experiments in which glucose oxidase was immobilized in porous glass supports are consistent with model simulations.

Original language	English
Pages (from-to)	1088-1098
Number of pages	11
Journal	AIChE Journal
Volume	32
Issue number	7
DOIs	https://doi.org/10.1002/aic.690320705
Publication status	Published - Jul 1986
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Environmental Engineering
General Chemical Engineering

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10.1002/aic.690320705

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abstract = "A restricted diffusion model is developed to study the immobilization of enzyme in porous solid supports. Simulation studies have been carried out for various combinations of process variables and parameters of the immobilization system. The model has also been used to develop a method for estimating the intrinsic rate constant of immobilization when enzyme diffusion into the support is restricted. Results of experiments in which glucose oxidase was immobilized in porous glass supports are consistent with model simulations.",

author = "Hossain, {Md M.} and Do, {D. D.} and Bailey, {J. E.}",

year = "1986",

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Immobilization of enzymes in porous solids under restricted diffusion conditions

Abstract

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