TY - JOUR
T1 - Impact of COVID-19 Vaccination on the Trend of Hospital Admission and Mortality in Two Tertiary Care Hospitals in the United Arab Emirates
T2 - A Retrospective Study
AU - Pradhan, Rohit
AU - Ahmed, Luai A.
AU - Kaabi, Nawal Al
AU - Subki, Waddah Ibrahim El
AU - Zaabi, Ashraf Al
N1 - Funding Information:
The study was funded by an educational unrestricted grant from Zayed Military Hospital.
Funding Information:
The study was funded by an educational unrestricted grant from Zayed Military Hospital.We would like to thank the CTI Clinical Trial and Consulting Services for their efforts in editing this manuscript.
Publisher Copyright:
© 2023 The Author(s). Published by Bentham Science Publisher.
PY - 2023
Y1 - 2023
N2 - Objectives: To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. Methods: We included patients admitted to two tertiary hospitals from October 2020 to July 2022. Patients were categorized into non-vaccinated, partially-vaccinated, and fully-vaccinated groups. Results: A total of 2277 cases were included, with 27.49% being non-vaccinated. The monthly trend of admitted patients dropped from 1264 (56.50%) cases in the first half of 2021 to 194 (8.67%) cases in the first half of 2022, with a reduction rate of 84.65%. The trend of ICU admission followed the overall hospital admission rate, with an overall CFR of 0.88%, 95% CI (0.54% to 1.35%), and a virulence rate of 1.76%, 95% CI (1.26% to 2.38%). The incidence of ICU admission in the unvaccinated group was 4.79%, compared to 0% and 0.97% in the partially-vaccinated and fully-vaccinated groups, respectively (p <0.001). The CFR was significantly (p <0.001) higher in the unvaccinated group 2.88%, 95% CI (1.71 to 4.51) than in the partially-vaccinated 0%, 95% CI (0% to 0.59%) and fully-vaccinated groups 0.19%, 95% CI (0.02% to 0.70%). Conclusion: Among the study population, COVID-19 vaccines showed promising efficacy in reducing the trend of COVID-19-related hospitalization, ICU admission, and mortality. Full vaccination might reduce the burden of COVID-19 on healthcare.
AB - Objectives: To investigate the impact of COVID-19 vaccines in the United Arab Emirates (UAE) on the trend of COVID-19-related hospitalization, intensive care unit (ICU) admissions, and case fatality rate (CFR), this retrospective chart review was conducted. Methods: We included patients admitted to two tertiary hospitals from October 2020 to July 2022. Patients were categorized into non-vaccinated, partially-vaccinated, and fully-vaccinated groups. Results: A total of 2277 cases were included, with 27.49% being non-vaccinated. The monthly trend of admitted patients dropped from 1264 (56.50%) cases in the first half of 2021 to 194 (8.67%) cases in the first half of 2022, with a reduction rate of 84.65%. The trend of ICU admission followed the overall hospital admission rate, with an overall CFR of 0.88%, 95% CI (0.54% to 1.35%), and a virulence rate of 1.76%, 95% CI (1.26% to 2.38%). The incidence of ICU admission in the unvaccinated group was 4.79%, compared to 0% and 0.97% in the partially-vaccinated and fully-vaccinated groups, respectively (p <0.001). The CFR was significantly (p <0.001) higher in the unvaccinated group 2.88%, 95% CI (1.71 to 4.51) than in the partially-vaccinated 0%, 95% CI (0% to 0.59%) and fully-vaccinated groups 0.19%, 95% CI (0.02% to 0.70%). Conclusion: Among the study population, COVID-19 vaccines showed promising efficacy in reducing the trend of COVID-19-related hospitalization, ICU admission, and mortality. Full vaccination might reduce the burden of COVID-19 on healthcare.
KW - COVID-19
KW - Fatality rate
KW - Hospital
KW - Intensive care
KW - Mortality
KW - Vaccine
UR - http://www.scopus.com/inward/record.url?scp=85167611072&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85167611072&partnerID=8YFLogxK
U2 - 10.2174/04666230316121757
DO - 10.2174/04666230316121757
M3 - Article
AN - SCOPUS:85167611072
SN - 0250-6882
VL - 4
JO - New Emirates Medical Journal
JF - New Emirates Medical Journal
IS - 2
M1 - e160323214688
ER -
