TY - JOUR
T1 - Impact of trauma system structure on injury outcomes
T2 - A systematic review protocol
AU - on behalf of the International Injury Care Improvement Initiative
AU - Moore, Lynne
AU - Champion, Howard
AU - O'Reilly, Gerard
AU - Leppaniemi, Ari
AU - Cameron, Peter
AU - Palmer, Cameron
AU - Abu-Zidan, Fikri M.
AU - Gabbe, Belinda
AU - Gaarder, Christine
AU - Yanchar, Natalie
AU - Stelfox, Henry Thomas
AU - Coimbra, Raul
AU - Kortbeek, John
AU - Noonan, Vanessa
AU - Gunning, Amy
AU - Leenan, Luke
AU - Gordon, Malcolm
AU - Khajanchi, Monty
AU - Shemilt, Michèle
AU - Porgo, Valérie
AU - Turgeon, Alexis F.
N1 - Publisher Copyright:
© 2017 The Author(s).
PY - 2017/1/21
Y1 - 2017/1/21
N2 - Background: Injury represents one of the greatest public health challenges of our time with over 5 million deaths and 100 million people temporarily or permanently disabled every year worldwide. The effectiveness of trauma systems in decreasing injury mortality and morbidity has been well demonstrated. However, the organisation of trauma care varies significantly across trauma systems and we know little about which components of trauma systems contribute to their effectiveness. The objective of the study described in this protocol is to systematically review evidence of the impact of trauma system components on clinically significant outcomes including mortality, function and disability, quality of life, and resource utilization. Methods: We will perform a systematic review of studies evaluating the association between at least one trauma system component (e.g. accreditation by a central agency, interfacility transfer agreements) and at least one injury outcome (e.g. mortality, disability, resource use). We will search MEDLINE, EMBASE, COCHRANE central, and BIOSIS/Web of Knowledge databases, thesis holdings, key injury organisation websites and conference proceedings for eligible studies. Pairs of independent reviewers will evaluate studies for eligibility and extract data from included articles. Methodological quality will be evaluated using elements of the ROBINS-I tool and the Cochrane risk of bias tool for non-randomized and randomized studies, respectively. Strength of evidence will be evaluated using the GRADE tool. Discussion: We expect to advance knowledge on the components of trauma systems that contribute to their effectiveness. This may lead to recommendations on trauma system structure that will help policy-makers make informed decisions as to where resources should be focused. The review may also lead to specific recommendations for future research efforts. Systematic review registration: This protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 28-06-2016. PROSPERO 2016:CRD42016041336 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016041336.
AB - Background: Injury represents one of the greatest public health challenges of our time with over 5 million deaths and 100 million people temporarily or permanently disabled every year worldwide. The effectiveness of trauma systems in decreasing injury mortality and morbidity has been well demonstrated. However, the organisation of trauma care varies significantly across trauma systems and we know little about which components of trauma systems contribute to their effectiveness. The objective of the study described in this protocol is to systematically review evidence of the impact of trauma system components on clinically significant outcomes including mortality, function and disability, quality of life, and resource utilization. Methods: We will perform a systematic review of studies evaluating the association between at least one trauma system component (e.g. accreditation by a central agency, interfacility transfer agreements) and at least one injury outcome (e.g. mortality, disability, resource use). We will search MEDLINE, EMBASE, COCHRANE central, and BIOSIS/Web of Knowledge databases, thesis holdings, key injury organisation websites and conference proceedings for eligible studies. Pairs of independent reviewers will evaluate studies for eligibility and extract data from included articles. Methodological quality will be evaluated using elements of the ROBINS-I tool and the Cochrane risk of bias tool for non-randomized and randomized studies, respectively. Strength of evidence will be evaluated using the GRADE tool. Discussion: We expect to advance knowledge on the components of trauma systems that contribute to their effectiveness. This may lead to recommendations on trauma system structure that will help policy-makers make informed decisions as to where resources should be focused. The review may also lead to specific recommendations for future research efforts. Systematic review registration: This protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 28-06-2016. PROSPERO 2016:CRD42016041336 Available from http://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016041336.
KW - Injury outcomes
KW - Organizational-level intervention
KW - Trauma system
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U2 - 10.1186/s13643-017-0408-8
DO - 10.1186/s13643-017-0408-8
M3 - Article
C2 - 28109306
AN - SCOPUS:85009957646
SN - 2046-4053
VL - 6
JO - Systematic reviews
JF - Systematic reviews
IS - 1
M1 - 12
ER -