Improved plasma membrane expression of the trafficking defective P344R mutant of muscle, skeletal, receptor tyrosine kinase (MuSK) causing congenital myasthenic syndrome

Medicine & Life Sciences

• Calnexin 13%
• Cell Line 5%
• Cell Membrane 46%
• Congenital Myasthenic Syndromes 100%
• COS Cells 10%
• Curcumin 10%
• Cysteine 8%
• Dimethyl Sulfoxide 10%
• Endoplasmic Reticulum 25%
• Endoplasmic Reticulum-Associated Degradation 13%
• Glycerol 9%
• Glycosylation 9%
• Half-Life 8%
• HEK293 Cells 9%
• Maintenance 6%
• Membranes 5%
• Missense Mutation 9%
• Mutant Proteins 29%
• Mutation 10%
• Neuromuscular Junction 10%
• Protein Domains 9%
• Proteins 9%
• Receptor Protein-Tyrosine Kinases 67%
• Skeletal Muscle 50%
• Thapsigargin 11%
• Therapeutics 1%

Chemical Compounds

• Chemical Compound 9%
• Curcumin 10%
• Dimethyl Sulfoxide 8%
• Glycerol 7%
• Marker 7%
• Mutation 22%
• Neuromuscular 12%
• Plasma 38%
• Protein 26%
• Protein Synthesis 9%
• Reaction Half Life 8%
• Tertiary Structure 9%
• Thapsigargin 13%
• Tyrosine 57%