Increased striatal gray matter densities in patients with schizophrenia and substance use disorder: A voxel-based morphometry study

Stéphane Potvin; Adham Mancini-Marïe; Chérine Fahim; Boualem Mensour; Johanne Lévesque; Sherif Karama; Mario Beauregard; Pierre Paul Rompré; Emmanuel Stip

doi:10.1016/j.pscychresns.2006.11.009

Increased striatal gray matter densities in patients with schizophrenia and substance use disorder: A voxel-based morphometry study

Stéphane Potvin
, Adham Mancini-Marïe
, Chérine Fahim
, Boualem Mensour
, Johanne Lévesque
, Sherif Karama
, Mario Beauregard
, Pierre Paul Rompré
, Emmanuel Stip

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

We sought to investigate the link between substance abuse and increased striatal gray matter densities (GMD) in schizophrenia, using voxel-based morphometry (VBM). Increased striatal GMD were found in patients with schizophrenia and substance use disorder (n = 12), but not schizophrenia only patients (n = 11), compared to healthy volunteers (n = 15).

Original language	English
Pages (from-to)	275-279
Number of pages	5
Journal	Psychiatry Research - Neuroimaging
Volume	154
Issue number	3
DOIs	https://doi.org/10.1016/j.pscychresns.2006.11.009
Publication status	Published - Apr 15 2007
Externally published	Yes

Keywords

Schizophrenia
Substance use disorders
Voxel-based morphometry

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

Access to Document

10.1016/j.pscychresns.2006.11.009

Cite this

Potvin, S, Mancini-Marïe, A, Fahim, C, Mensour, B, Lévesque, J, Karama, S, Beauregard, M, Rompré, PP & Stip, E 2007, 'Increased striatal gray matter densities in patients with schizophrenia and substance use disorder: A voxel-based morphometry study', Psychiatry Research - Neuroimaging, vol. 154, no. 3, pp. 275-279. https://doi.org/10.1016/j.pscychresns.2006.11.009

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abstract = "We sought to investigate the link between substance abuse and increased striatal gray matter densities (GMD) in schizophrenia, using voxel-based morphometry (VBM). Increased striatal GMD were found in patients with schizophrenia and substance use disorder (n = 12), but not schizophrenia only patients (n = 11), compared to healthy volunteers (n = 15).",

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doi = "10.1016/j.pscychresns.2006.11.009",

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AU - Potvin, Stéphane

AU - Mancini-Marïe, Adham

AU - Fahim, Chérine

AU - Mensour, Boualem

AU - Lévesque, Johanne

AU - Karama, Sherif

AU - Beauregard, Mario

AU - Rompré, Pierre Paul

AU - Stip, Emmanuel

N1 - Funding Information: This study was supported by grants from the Fonds de la Recherche en Santé du Québec (FRSQ), AstraZeneca Pharmaceuticals, University of Montreal Eli Lilly Chair of Schizophrenia Fund and the Canadian Institute of Health Research (CIHR). The authors would like to thank Lahcen Aït Bentaleb M.D., Pierre Lalonde M.D., Marcel Wolfe M.D. and Jean M'Pania M.D. for their assistance in patient recruitment.

PY - 2007/4/15

Y1 - 2007/4/15

N2 - We sought to investigate the link between substance abuse and increased striatal gray matter densities (GMD) in schizophrenia, using voxel-based morphometry (VBM). Increased striatal GMD were found in patients with schizophrenia and substance use disorder (n = 12), but not schizophrenia only patients (n = 11), compared to healthy volunteers (n = 15).

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KW - Schizophrenia

KW - Substance use disorders

KW - Voxel-based morphometry

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JF - Psychiatry Research - Neuroimaging

IS - 3

ER -

Increased striatal gray matter densities in patients with schizophrenia and substance use disorder: A voxel-based morphometry study

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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