INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

G. R. Greenberg, T. E. Adrian, J. H. Baron, R. F. Mccloy, V. S. Chadwick, S. R. Bloom

Research output: Contribution to journalArticlepeer-review

152 Citations (Scopus)

Abstract

Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

Original languageEnglish
Pages (from-to)1280-1282
Number of pages3
JournalThe Lancet
Volume312
Issue number8103
DOIs
Publication statusPublished - Dec 16 1978
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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