INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

G. R. Greenberg; T. E. Adrian; J. H. Baron; R. F. Mccloy; V. S. Chadwick; S. R. Bloom

doi:10.1016/S0140-6736(78)92042-1

INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

G. R. Greenberg, T. E. Adrian, J. H. Baron, R. F. Mccloy, V. S. Chadwick, S. R. Bloom

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157 Citations (Scopus)

Abstract

Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

Original language	English
Pages (from-to)	1280-1282
Number of pages	3
Journal	The Lancet
Volume	312
Issue number	8103
DOIs	https://doi.org/10.1016/S0140-6736(78)92042-1
Publication status	Published - Dec 16 1978
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1016/S0140-6736(78)92042-1

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title = "INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE",

abstract = "Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.",

author = "Greenberg, {G. R.} and Adrian, {T. E.} and Baron, {J. H.} and Mccloy, {R. F.} and Chadwick, {V. S.} and Bloom, {S. R.}",

year = "1978",

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T1 - INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

AU - Greenberg, G. R.

AU - Adrian, T. E.

AU - Baron, J. H.

AU - Mccloy, R. F.

AU - Chadwick, V. S.

AU - Bloom, S. R.

PY - 1978/12/16

Y1 - 1978/12/16

N2 - Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

AB - Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

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U2 - 10.1016/S0140-6736(78)92042-1

DO - 10.1016/S0140-6736(78)92042-1

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JO - The Lancet

JF - The Lancet

IS - 8103

ER -

INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

Abstract

ASJC Scopus subject areas

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