INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

G. R. Greenberg; T. E. Adrian; J. H. Baron; R. F. Mccloy; V. S. Chadwick; S. R. Bloom

doi:10.1016/S0140-6736(78)92042-1

INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

G. R. Greenberg
, T. E. Adrian
, J. H. Baron
, R. F. Mccloy
, V. S. Chadwick
, S. R. Bloom

Research output: Contribution to journal › Article › peer-review

160 Citations (Scopus)

Abstract

Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

Original language	English
Pages (from-to)	1280-1282
Number of pages	3
Journal	The Lancet
Volume	312
Issue number	8103
DOIs	https://doi.org/10.1016/S0140-6736(78)92042-1
Publication status	Published - Dec 16 1978
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE",

abstract = "Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.",

author = "Greenberg, \{G. R.\} and Adrian, \{T. E.\} and Baron, \{J. H.\} and Mccloy, \{R. F.\} and Chadwick, \{V. S.\} and Bloom, \{S. R.\}",

year = "1978",

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doi = "10.1016/S0140-6736(78)92042-1",

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T1 - INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

AU - Greenberg, G. R.

AU - Adrian, T. E.

AU - Baron, J. H.

AU - Mccloy, R. F.

AU - Chadwick, V. S.

AU - Bloom, S. R.

PY - 1978/12/16

Y1 - 1978/12/16

N2 - Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

AB - Stimulated pancreatic and biliary outputs were studied in seven healthy subjects during intravenous infusion of bovine pancreatic polypeptide (P.P.) (mean dose 65 pmol/kg/h). P.P. significantly inhibited outputs of trypsin and bilirubin at plasma concentrations similar to those observed after meals. In four cholecystectomised subjects, P.P. inhibited only trypsin output.

UR - https://www.scopus.com/pages/publications/0018224109

UR - https://www.scopus.com/pages/publications/0018224109#tab=citedBy

U2 - 10.1016/S0140-6736(78)92042-1

DO - 10.1016/S0140-6736(78)92042-1

M3 - Article

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AN - SCOPUS:0018224109

SN - 0140-6736

VL - 312

SP - 1280

EP - 1282

JO - The Lancet

JF - The Lancet

IS - 8103

ER -

INHIBITION OF PANCREAS AND GALLBLADDER BY PANCREATIC POLYPEPTIDE

Abstract

ASJC Scopus subject areas

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