Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla)

J. Michael Conlon; Lars Thim

doi:10.1016/0305-0491(89)90092-8

Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla)

J. Michael Conlon
, Lars Thim

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

1. 1. The primary structure of the C-peptide of proinsulin from the European eel has been established as: {A figure is presented} 2. 2. The peptide was isolated from the extract of eel pancreas in a yield that was approximately equimolar with insulin. 3. 3. A comparison with the predicted structures of C-peptides from other teleost fishes has identified a domain in the central region of the peptide that has been more highly conserved than the rest of the molecule.

Original language	English
Pages (from-to)	359-362
Number of pages	4
Journal	Comparative biochemistry and physiology. B, Comparative biochemistry
Volume	93
Issue number	2
DOIs	https://doi.org/10.1016/0305-0491(89)90092-8
Publication status	Published - 1989
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physiology
Molecular Biology

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10.1016/0305-0491(89)90092-8

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title = "Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla)",

abstract = "1. 1. The primary structure of the C-peptide of proinsulin from the European eel has been established as: \{A figure is presented\} 2. 2. The peptide was isolated from the extract of eel pancreas in a yield that was approximately equimolar with insulin. 3. 3. A comparison with the predicted structures of C-peptides from other teleost fishes has identified a domain in the central region of the peptide that has been more highly conserved than the rest of the molecule.",

author = "Conlon, \{J. Michael\} and Lars Thim",

note = "Funding Information: Acknowledgements--This work was supported by the Stiftung Volkswagenwerk. The authors thank Drs N. Hazon and L. O'Toole, Gatty Marine Laboratory, St. Andrews, UK, and Drs C. F. Deacon and I. W. Henderson, University of Sheffield, UK, for providing the eel pancreatic tissues.",

year = "1989",

doi = "10.1016/0305-0491(89)90092-8",

language = "English",

volume = "93",

pages = "359--362",

journal = "Comparative biochemistry and physiology. B, Comparative biochemistry",

issn = "0305-0491",

publisher = "Elsevier BV",

number = "2",

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T1 - Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla)

AU - Conlon, J. Michael

AU - Thim, Lars

N1 - Funding Information: Acknowledgements--This work was supported by the Stiftung Volkswagenwerk. The authors thank Drs N. Hazon and L. O'Toole, Gatty Marine Laboratory, St. Andrews, UK, and Drs C. F. Deacon and I. W. Henderson, University of Sheffield, UK, for providing the eel pancreatic tissues.

PY - 1989

Y1 - 1989

N2 - 1. 1. The primary structure of the C-peptide of proinsulin from the European eel has been established as: {A figure is presented} 2. 2. The peptide was isolated from the extract of eel pancreas in a yield that was approximately equimolar with insulin. 3. 3. A comparison with the predicted structures of C-peptides from other teleost fishes has identified a domain in the central region of the peptide that has been more highly conserved than the rest of the molecule.

AB - 1. 1. The primary structure of the C-peptide of proinsulin from the European eel has been established as: {A figure is presented} 2. 2. The peptide was isolated from the extract of eel pancreas in a yield that was approximately equimolar with insulin. 3. 3. A comparison with the predicted structures of C-peptides from other teleost fishes has identified a domain in the central region of the peptide that has been more highly conserved than the rest of the molecule.

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DO - 10.1016/0305-0491(89)90092-8

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AN - SCOPUS:0024326663

SN - 0305-0491

VL - 93

SP - 359

EP - 362

JO - Comparative biochemistry and physiology. B, Comparative biochemistry

JF - Comparative biochemistry and physiology. B, Comparative biochemistry

IS - 2

ER -

Isolation and primary structure of the C-peptide of proinsulin from the European eel (Anguilla anguilla)

Abstract

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