Isolation and structure of guinea pig gastric and pancreatic somatostatin

J. Michael Conlon

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


Somatostatin-14 has been isolated from guinea pig pancreas and stomach and purified to homogeneity by gel filtration, ion-exchange chromatography and reverse phase HPLC. Amino acid composition and sequence analysis indicated that guinea pig somatostatin from both tissues has the same structure as somatostatin-14 from all other mammalian species yet studied. The study has demonstrated that somatostatin-14 from gastric tissue has the same structure as the peptide from hypothalamus and pancreas.

Original languageEnglish
Pages (from-to)213-220
Number of pages8
JournalLife Sciences
Issue number2
Publication statusPublished - Jul 9 1984
Externally publishedYes

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry,Genetics and Molecular Biology


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