Les médicaments antipsychotiques: Facteurs de risque de diabète

Translated title of the contribution: Antipsychotic drugs: Risk factors for diabetes

Emmanuel Stip, Constantin Tranulis, Nancy Légaré, Marie Josée Poulin

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Antipsychotics and diabetes: After 50 years' use of antipsychotics, it is pertinent to draw-up a circumspect review of the side effects of these psychotropic agents. Moreover, few articles have attempted to elucidate the relationship between the monitoring of carbohydrate metabolism and the prescription of this type of medication. Several mechanisms at the origin of an imbalance in glycaemia: Antipsychotics, notably the atypical forms, represent an additional factor of risk for developing diabetes. The weight gain secondary to this treatment plays an important part in this imbalance, but other mechanisms may also contribute. Depending on the type of antipsychotic: Our present knowledge is insufficient to be able to quantify the effect of each atypical antipsychotic on diabetes. The only tendency that has been reproduced in several studies concerns the increased risk associated with dibenzodiazepine antipsychotics (clozapine and olanzapine), compared with the other antipsychotics.

Translated title of the contributionAntipsychotic drugs: Risk factors for diabetes
Original languageFrench
Pages (from-to)1612-1617
Number of pages6
JournalPresse Medicale
Issue number34
Publication statusPublished - Oct 18 2003
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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