Linkage mapping of the [Pro2]somatostatin-14 gene in zebrafish: Evolutionary perspectives

Hervé Tostivint, Lucille Joly, Isabelle Lihrmann, J. Michael Conlon, Marc Ekker, Hubert Vaudry

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Radiation hybrid mapping assigned the zebrafish [Pro2] somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.

Original languageEnglish
Pages (from-to)486-489
Number of pages4
JournalAnnals of the New York Academy of Sciences
Volume1040
DOIs
Publication statusPublished - 2005
Externally publishedYes

Keywords

  • Comparative genomics
  • Cortistatin
  • Evolution
  • Radiation hybrid mapping
  • Somatostatin
  • Zebrafish

ASJC Scopus subject areas

  • General Neuroscience
  • General Biochemistry,Genetics and Molecular Biology
  • History and Philosophy of Science

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