Lipid and Glucose Profile across Different Mental Disorders

Derar H. Abdel-Qader, Abdullah Albassam, Esra’ Taybeh, Nadia Al Mazrouei, Sara Murad Albarkat Meer, Khalid Awad Al-Kubaisi, Rana Ibrahim, Asim Ahmed Elnour, Osama Mohamed Ibrahim, Salah AbuRuz

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Schizophrenia, unipolar depression, bipolar disorder, bipolar mania, and bipolar depression are a few of the severe psychiatric diseases that affect millions of individuals and their overall life quality. This study aimed to look at differences in TGA, TC, HDL, LDL, and FPG levels in people who were going through acute episodes of listed diseases. Materials and methods: A cross-sectional prospective study was carried out in Jordan between January and November of 2023, involving all patients with the aforementioned diseases who attended three psychiatric clinics. This study encompassed results from 1187 patients (women N = 675, 56.87%) who were classified into the following ranges: <25, 25–45, 45–65, and >65. Results: The average level of LDL was the highest in bipolar depression (112.442 ± 36.178 mg/dL) and the lowest in bipolar mania (111.25 ± 33.14 mg/dL). The average level of HDL was the highest in schizophrenia (58.755 ± 16.198 mg/dL) and the lowest in bipolar depression (45.584 ± 12.128 mg/dL). Both average levels of TC and TGA were the highest in patients with bipolar depression (188.403 ± 37.396 mg/dL and 149.685 ± 96.951 mg/dL, respectively) and the lowest in bipolar mania (164.790 ± 40.488 mg/dL and 100.679 ± 54.337 mg/dL, respectively). The average level of FPG was the highest in unipolar depression (94.00 ± 21.453 mg/dL) and the lowest in bipolar mania (89.492 ± 14.700 mg/dL). Conclusions: The results confirmed that lipid and glucose abnormalities were more common in people with schizophrenia and mood disorders (unipolar and bipolar).

Original languageEnglish
Article number2499
JournalJournal of Clinical Medicine
Volume13
Issue number9
DOIs
Publication statusPublished - May 2024

Keywords

  • bipolar depression
  • bipolar disorder
  • bipolar mania
  • lipid and glucose levels
  • schizophrenia
  • unipolar depression

ASJC Scopus subject areas

  • General Medicine

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