Lipid peroxidation in workers exposed to aluminium, gallium, indium, arsenic, and antimony in the optoelectronic industry

Yen Hsiung Liao, Long Chih Hwang, Jing Shwu Kao, Shuenn Jiun Yiin, Shu Fang Lin, Chia Hong Lin, Yu Cheng Lin, Tar Ching Aw

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

OBJECTIVE: The objective of this study was to investigate whether exposure to aluminum, gallium, indium, arsenic, and antimony induces lipid peroxidation in humans. METHODS: Whole blood and urine levels of 103 exposed electronic industry workers and 67 referents were analyzed by use of inductively coupled plasma mass spectrometry. Malondialdehyde (MDA), the product of lipid peroxidation, was determined by high-performance liquid chromatography. RESULTS: The mean plasma MDA level in the 103 workers was significantly higher than that in 67 referents. The levels of MDA in the exposed workers were correlated significantly with the levels of urinary gallium and arsenic. CONCLUSIONS: Malondialdehyde as an index of lipid peroxidation can be induced by gallium and arsenic exposure. By reducing exposure to these metals, biologic effects such as lipid peroxidation may also be diminished.

Original languageEnglish
Pages (from-to)789-793
Number of pages5
JournalJournal of Occupational and Environmental Medicine
Volume48
Issue number8
DOIs
Publication statusPublished - Aug 2006
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Fingerprint

Dive into the research topics of 'Lipid peroxidation in workers exposed to aluminium, gallium, indium, arsenic, and antimony in the optoelectronic industry'. Together they form a unique fingerprint.

Cite this