Localization of the IGHG, PRKACB, and TNP2 genes in pigs by in situ hybridization

F. Gu, B. P. Chowdhary, M. Johansson, L. Andersson, I. Gustavsson

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13 Citations (Scopus)


The porcine genes encoding the immunoglobulin gamma heavy chain (IGHG), cAMP-dependent protein kinase catalytic beta subunit (PRKACB), and transition protein 2 (TNP2) were mapped to Chromosomes (Chrs) 7 q25-q26, 6q31-q33, and 3p13-cent, respectively, by in situ hybridization. Localization of the IGHG gene confirms the assignment of linkage group III to Chr 7. Our results show that the IGHG locus in pigs, similar to the situation in other mammalian species, viz. humans, mouse, cattle, and river buffaloes, is located on the terminal region of the chromosome. The assignment of the PRKACB gene extends the homology observed between porcine Chr 6q and human Chr 1p. Mapping of the TNP2 gene provides the first marker assigned to the p arm of Chr 3 in pigs. The present study contributes to the development of the physical gene map in pigs and also bears significance in terms of comparative gene mapping.

Original languageEnglish
Pages (from-to)195-198
Number of pages4
JournalMammalian Genome
Issue number4
Publication statusPublished - Apr 1994
Externally publishedYes

ASJC Scopus subject areas

  • Genetics


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