Major artery occlusion: A rare complication of sickle cell disease

Adnan Agha, Mohammad Al-Hakami, Ghulam Shabbir

Research output: Contribution to journalArticlepeer-review


Sickle cell disease is hereditary hemoglobinopathy which causes haemolytic anemia, vaso-occlusive crisis, ischemic injuries and many other morbidities like cerebral infarction. In this report, we describe a case of a young patient with sickle cell disease presenting with right-sided weakness and slurring of speech with examination confirming right-sided hemiparesis with motor aphasia. On further investigation, she was found to have frontotemporal infarction. On magnetic resonance imaging with angiography, she was found to have absent circulation in left internal carotid artery probably secondary to sickle cell disease. Major vessel occlusion is rare complication of sickle cell disease that one must bear in mind.

Original languageEnglish
Article numbere2010007
JournalMediterranean Journal of Hematology and Infectious Diseases
Issue number1
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Hematology
  • Infectious Diseases


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