TY - JOUR
T1 - Management and 1-Year Outcomes of Patients With Atrial Fibrillation in the Middle East
T2 - Gulf Survey of Atrial Fibrillation Events
AU - Gulf Survey of Atrial Fibrillation Events (Gulf SAFE) Investigators
AU - Zubaid, Mohammad
AU - Rashed, Wafa A.
AU - Alsheikh-Ali, Alawi A.
AU - Al-Zakwani, Ibrahim
AU - AlMahmeed, Wael
AU - Shehab, Abdullah
AU - Sulaiman, Kadhim
AU - Qudaimi, Ahmed Al
AU - Asaad, Nidal
AU - Amin, Haitham
N1 - Publisher Copyright:
© The Author(s) 2014.
PY - 2015/5/21
Y1 - 2015/5/21
N2 - We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as hypertension (59%), diabetes (33%), and coronary artery disease (33%). Warfarin was not prescribed to 40% of patients with Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke/TIA2 score of ≥2. One-year rates of stroke/transient ischemic attack (TIA) and all-cause mortality were 4.2% and 15.3%, respectively. Warfarin use at hospital-ED discharge was independently associated with lower 1-year rate of stroke/TIA (odds ratio [OR], 0.38; 95% confidence interval [CI], 0.17-0.85; P =.015) and all-cause mortality (OR, 0.51; 95% CI, 0.32-0.83; P =.006). Prior history of heart failure and peripheral vascular disease was independent mortality predictors. Our patients are relatively young with significant cardiovascular risk. Their anticoagulation treatment is suboptimal, and 1-year all-cause mortality and stroke/TIA event rates are relatively high.
AB - We describe management and outcomes of patients with nonvalvular atrial fibrillation (AF) in the Middle East. Consecutive patients with AF presenting to emergency departments (EDs) were prospectively enrolled. Among 1721 patients with nonvalvular AF, mean age was 59 ± 16 years and 44% were women. Comorbidities were common such as hypertension (59%), diabetes (33%), and coronary artery disease (33%). Warfarin was not prescribed to 40% of patients with Congestive heart failure, Hypertension, Age, Diabetes mellitus, Stroke/TIA2 score of ≥2. One-year rates of stroke/transient ischemic attack (TIA) and all-cause mortality were 4.2% and 15.3%, respectively. Warfarin use at hospital-ED discharge was independently associated with lower 1-year rate of stroke/TIA (odds ratio [OR], 0.38; 95% confidence interval [CI], 0.17-0.85; P =.015) and all-cause mortality (OR, 0.51; 95% CI, 0.32-0.83; P =.006). Prior history of heart failure and peripheral vascular disease was independent mortality predictors. Our patients are relatively young with significant cardiovascular risk. Their anticoagulation treatment is suboptimal, and 1-year all-cause mortality and stroke/TIA event rates are relatively high.
KW - Middle East
KW - anticoagulation
KW - atrial fibrillation
KW - risk assessment
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=84928010789&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84928010789&partnerID=8YFLogxK
U2 - 10.1177/0003319714536980
DO - 10.1177/0003319714536980
M3 - Article
C2 - 24904179
AN - SCOPUS:84928010789
SN - 0003-3197
VL - 66
SP - 464
EP - 471
JO - Angiology
JF - Angiology
IS - 5
ER -