Medicinal chemistry of drugs with active metabolites (N-, O-, and S-desalkylation and some specific oxidative alterations)

Pharmacology, Toxicology and Pharmaceutical Science

• Active Metabolite 100%
• Pharmaceutical Chemistry 100%
• Alkyl Group 100%
• Elimination 50%
• Paracetamol 50%
• Cytochrome P450 50%
• Enzymes 50%
• Lipophilicity 50%
• Cytochrome 50%
• Therapeutic Drug Monitoring 50%
• Phenacetin 50%
• Mixed Function Oxidase 50%
• Aldehyde 50%
• Hydrophile 50%
• Amine 50%

Chemistry

• Metabolite 100%
• Chemistry 100%
• Metabolic 40%
• Alkyl Group 40%
• Pharmacological Effect 20%
• Paracetamol 20%
• Amino Group 20%
• Logp 20%
• Cytochrome 20%
• Mixed Function Oxidase 20%
• Lipophilicity 20%
• Hydroxyl 20%
• Phenacetin 20%
• Aldehyde 20%
• Amine 20%
• Hydrophile 20%
• Cytochrome P450 20%

Keyphrases

• Active Pharmaceutical Ingredients 33%
• P450 Cytochromes 33%
• Free Hydroxyl Groups 33%