Medicinal chemistry of drugs with active metabolites (N-, O-, and S-desalkylation and some specific oxidative alterations)

Keyphrases

• Alkyl Group 66%
• Phenacetin 33%
• Active Compounds 33%
• Therapeutic Drug Monitoring 33%
• Hepatic Cytochrome P450 33%
• Metabolic Fate 33%
• Mixed Function Oxidases 33%
• Oxidase Enzymes 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Alkyl Group 100%
• Phenacetin 50%
• Mixed Function Oxidase 50%

Chemistry

• Alkyl Group 40%
• Logp 20%
• Cytochrome 20%
• Mixed Function Oxidase 20%
• Lipophilicity 20%
• Hydroxyl 20%
• Phenacetin 20%