TY - JOUR
T1 - Melanin is a plenteous bioactive phenolic compound in date fruits (Phoenix dactylifera L.)
AU - Alam, Muneeba Zubair
AU - Ramachandran, Tholkappiyan
AU - Antony, Asha
AU - Hamed, Fathalla
AU - Ayyash, Mutamed
AU - Kamal-Eldin, Afaf
N1 - Funding Information:
The authors are grateful to Al Foah Dates Factory (Al Saad, Al Ain, United Arab Emirates, UAE) for providing date samples. Mr. Hussain Awad El Sayed (Department of Chemical and Petroleum, College of Engineering), Mr. Mohammed Tariq, and Ms. Nadia Alkalbani (Department of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, UAE) are thanked for providing technical support.
Funding Information:
This study was funded by United Arab Emirates University (UPAR grant 31F125).
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Date palm fruits (Phoenix dactylifera L.) were found to contain high levels of allomelanin (1.2–5.1%). The melanin is localized in the tanniferous cells between the inner and outer mesocarp tissues of the fruit. The melanin, extracted with 2 M sodium hydroxide, consisted of amorphous graphene-like granular structures of irregular shape and variable size. The date fruit melanin mainly comprises carbon (64.6%) and oxygen (30.6) but no nitrogen, and was thermally stable. It has radical scavenging (63.6–75.1 IC50, µg/mL), antimicrobial (250–1000 µg/mL), hypoglycemic (51.8–58.2%), and angiotensin-converting-enzyme inhibitory (65.8%) effects. The high level of melanin in date fruits highlights the importance of investigating its dietary intake and its impact on nutrition. This study also suggests that date fruit melanin can be a functional ingredient in foods, food packages, pharmaceuticals, and cosmetics.
AB - Date palm fruits (Phoenix dactylifera L.) were found to contain high levels of allomelanin (1.2–5.1%). The melanin is localized in the tanniferous cells between the inner and outer mesocarp tissues of the fruit. The melanin, extracted with 2 M sodium hydroxide, consisted of amorphous graphene-like granular structures of irregular shape and variable size. The date fruit melanin mainly comprises carbon (64.6%) and oxygen (30.6) but no nitrogen, and was thermally stable. It has radical scavenging (63.6–75.1 IC50, µg/mL), antimicrobial (250–1000 µg/mL), hypoglycemic (51.8–58.2%), and angiotensin-converting-enzyme inhibitory (65.8%) effects. The high level of melanin in date fruits highlights the importance of investigating its dietary intake and its impact on nutrition. This study also suggests that date fruit melanin can be a functional ingredient in foods, food packages, pharmaceuticals, and cosmetics.
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U2 - 10.1038/s41598-022-10546-9
DO - 10.1038/s41598-022-10546-9
M3 - Article
C2 - 35459886
AN - SCOPUS:85128721328
SN - 2045-2322
VL - 12
JO - Scientific reports
JF - Scientific reports
IS - 1
M1 - 6614
ER -