Melissa officinalis protects against doxorubicin-induced cardiotoxicity in rats and potentiates its anticancer activity on MCF-7 cells

Agriculture & Biology

• cardiotoxicity 88%
• Melissa officinalis 84%
• doxorubicin 73%
• rats 31%
• cells 18%
• breast neoplasms 13%
• neoplasm cells 10%
• cancer therapy 8%
• myeloperoxidase 7%
• prostaglandin synthase 6%
• tumor necrosis factor-alpha 6%
• albino 5%
• oxidants 5%
• in vitro studies 5%
• apoptosis 5%
• inflammation 5%
• lipid peroxidation 4%
• oxidative stress 4%
• heart 4%
• neoplasms 4%
• pretreatment 4%
• oxidation 4%
• protocols 4%
• antioxidants 3%
• extracts 3%
• dosage 3%
• enzymes 2%
• tissues 2%
• proteins 2%

Medicine & Life Sciences

• Melissa 100%
• Cardiotoxicity 67%
• MCF-7 Cells 64%
• Doxorubicin 55%
• Antineoplastic Protocols 10%
• Breast Neoplasms 7%
• NF-kappa B 6%
• Cyclooxygenase 2 6%
• Oxidants 6%
• Peroxidase 5%
• Lipid Peroxidation 5%
• Antioxidants 4%
• Oxidative Stress 4%
• Tumor Necrosis Factor-alpha 4%
• Heart 3%
• Apoptosis 3%
• Enzymes 3%
• In Vitro Techniques 2%
• Proteins 2%
• Therapeutics 0%

Chemical Compounds

• Doxorubicin 62%
• Once Daily 16%
• Apoptotic 11%
• Oxidative Stress 9%
• Dose 7%
• Lipid 6%
• Oxidation Reaction 4%
• Protein 4%