TY - JOUR
T1 - Microwave irradiation-assisted amination of 2-chloropyridine derivatives with amide solvents
AU - Samadi, Abdelouahid
AU - Silva, Daniel
AU - Chioua, Mourad
AU - Carreiras, Maria Do Carmo
AU - Marco-Contelles, José
N1 - Funding Information:
The present work has been supported by MEC Grant SAF2006-08764-C02-01, Comunidad de Madrid (S/SAL-0275-2006), Instituto de Salud Carlos III [RETIC RENEVAS (RD06/0026/1002)], and AECI (A/07492/07). A. S. thanks CSCI for the JAE-doc contract. M. C. thanks the Instituto de Salud Carlos III (Ministerio de Salud y Consumo) for a postdoctoral fellowship.
PY - 2011
Y1 - 2011
N2 - A simple, quick, and high-yielding microwave-assisted synthesis of 2-(N,Ndimethyl) amine- and 2-aminopyridine derivatives is reported here for the first time in the reaction of 2-chloro substituted pyridines with amide solvents such as dimethylformamide or formamide, without transition-metal catalysts.
AB - A simple, quick, and high-yielding microwave-assisted synthesis of 2-(N,Ndimethyl) amine- and 2-aminopyridine derivatives is reported here for the first time in the reaction of 2-chloro substituted pyridines with amide solvents such as dimethylformamide or formamide, without transition-metal catalysts.
KW - 2-(N, N-dimethyl)-aminopyridines
KW - 2-aminopyridines
KW - 2-chloropyridines
KW - Amides
KW - Amination
KW - Microwave irradiation
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U2 - 10.1080/00397911.2010.515360
DO - 10.1080/00397911.2010.515360
M3 - Article
AN - SCOPUS:79960014572
SN - 0039-7911
VL - 41
SP - 2859
EP - 2869
JO - Synthetic Communications
JF - Synthetic Communications
IS - 19
ER -