Modeling of enzyme immobilization in porous membranes

Md M. Hossain, D. D. Do

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


This article deals with the mathematical modeling of the process of enzyme immobilization in porous membranes. During the initial period, an analytical solution is available to extract the rate constant for immobilization. Beyond this period, the model equations are solved numerically to yield the transient response of the enzyme concentration in the immobilizing solution and also the evolution of the enzyme loading profile inside the membrane. It is found that the immobilization practically ceases even through the attachment sites are still available within the membrane.

Original languageEnglish
Pages (from-to)1126-1135
Number of pages10
JournalBiotechnology and Bioengineering
Issue number8
Publication statusPublished - Aug 1985
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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