@inproceedings{2a0e9ab7699d497282c5759b9e47b10b,

title = "Modeling particle-fluid coupling and its impact on magnetic particle transport in microfluidic systems",

abstract = "An analysis is presented of the effects of particle-fluid coupling on the transport and capture of magnetic particles in microfluidic systems with magnetophoretic functionality. Magnetic particle transport is modeled using a computational fluid dynamic CFD-based Lagrangian-Eulerian approach that takes into account dominant particle forces as well as two-way particle-fluid coupling. The difference in capture efficiency for one-way versus two-way particle-fluid coupling is analyzed and quantified. The analysis shows that one-way coupling over predicts the magnetic force needed for particle capture as compared to more rigorous fully-coupled analysis. In two-way coupling there is a cooperative effect between the magnetic force and a particle-induced flow towards regions of high field gradient that enhances capture efficiency. While commonly used one-way coupling is useful for rapid parametric screening of particle capture efficiency, more accurate predictions require two-way particle-fluid coupling. This is especially true when higher capture efficiencies and/or particle concentrations are required.",

keywords = "Field-directed particle transport, Magnetic particle transport, Magnetic separation, Magnetophoresis, Magnetophoretic microsystem, Particle-fluid coupling",

author = "Khashan, {Saud A.} and Furlani, {Edward P.}",

year = "2012",

month = aug,

day = "17",

language = "English",

isbn = "9781466562752",

series = "Technical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012",

pages = "408--411",

booktitle = "Nanotechnology 2012",

note = "Nanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 ; Conference date: 18-06-2012 Through 21-06-2012",

}