Modeling particle-fluid coupling and its impact on magnetic particle transport in microfluidic systems

Saud A. Khashan, Edward P. Furlani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

An analysis is presented of the effects of particle-fluid coupling on the transport and capture of magnetic particles in microfluidic systems with magnetophoretic functionality. Magnetic particle transport is modeled using a computational fluid dynamic CFD-based Lagrangian-Eulerian approach that takes into account dominant particle forces as well as two-way particle-fluid coupling. The difference in capture efficiency for one-way versus two-way particle-fluid coupling is analyzed and quantified. The analysis shows that one-way coupling over predicts the magnetic force needed for particle capture as compared to more rigorous fully-coupled analysis. In two-way coupling there is a cooperative effect between the magnetic force and a particle-induced flow towards regions of high field gradient that enhances capture efficiency. While commonly used one-way coupling is useful for rapid parametric screening of particle capture efficiency, more accurate predictions require two-way particle-fluid coupling. This is especially true when higher capture efficiencies and/or particle concentrations are required.

Original languageEnglish
Title of host publicationNanotechnology 2012
Subtitle of host publicationElectronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
Pages408-411
Number of pages4
Publication statusPublished - 2012
EventNanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012 - Santa Clara, CA, United States
Duration: Jun 18 2012Jun 21 2012

Publication series

NameTechnical Proceedings of the 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012

Other

OtherNanotechnology 2012: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2012 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2012
Country/TerritoryUnited States
CitySanta Clara, CA
Period6/18/126/21/12

Keywords

  • Field-directed particle transport
  • Magnetic particle transport
  • Magnetic separation
  • Magnetophoresis
  • Magnetophoretic microsystem
  • Particle-fluid coupling

ASJC Scopus subject areas

  • Ceramics and Composites
  • Surfaces, Coatings and Films

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