Wastewater discharges that contain dyes are one of the main water pollution sources in the world, where these essentially result from industrial processes. Hence, there are multiple processes to treat this wastewater, where one of them is the adoption process. In this study, the use of PVC-Lisinopril modified polymer as absorbent was investigated using two doses at room temperature. The effect of adsorption time on PH, conductivity, adsorption capacity (q), and removable efficiency (R%) were studied. Results showed that as the time increase, the impact on PH and conductivity of 50 mg adsorbent mass solution was higher than 30 mg solution, where higher acidity and conductivity were obtained. This was attributed to the increase in surface area and surface charge of the adsorbent, and the high ionization of MO. Also, the adsorption capacity and MO removal percentage increased as the mass of modified PVC amount increased. During the adsorption process, there are more active sites and available areas for adsorption when the amount of adsorbent was 50 mg comparing with 30 mg, where the abundance of active sites leads to having more capacity. Similarly, the removal ratio of dyes increases as the adsorbent weight increased from 30 to 50 mg, for the same explained reason. The removal ratio was 84% after 20 min of adsorption.