Multivariate analysis of gene expression data and missing value imputation based on llsimpute algorithm

Kohbalan Moorthy, Mohd Saberi Mohamad, Safaai Deris, Zuwairie Ibrahim

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Microarray ade4 or known as MADE4 is a multivariate software analysis package for microarray gene expression data. This software package is capable of accepting wide variety of gene expression data formats such as Bioconductor Affy Batch and exprSet. This MADE4 R package extends the advantages of ade4 package in multivariate statistical and graphical functions for the use in the microarray data application. Moreover, MADE4 provides new graphical and visualization tools that assist in the interpretation of multivariate analysis of microarray data. Besides that, LLSimpute algorithm has been incorporated to assist in handling of datasets with missing values and this has eased the application for the users to analysis on gene expression data that contain missing values.

Original languageEnglish
Pages (from-to)1335-1339
Number of pages5
JournalICIC Express Letters
Volume6
Issue number5
Publication statusPublished - May 2012
Externally publishedYes

Keywords

  • Between group analysis
  • Co-inertia analysis
  • Correspondence analysis
  • Gene expression data
  • Llsimpute algorithm
  • Microarray data
  • Multivariate analysis

ASJC Scopus subject areas

  • Control and Systems Engineering
  • General Computer Science

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