Myrcene Salvages Rotenone-Induced Loss of Dopaminergic Neurons by Inhibiting Oxidative Stress, Inflammation, Apoptosis, and Autophagy

Medicine & Life Sciences

• myrcene 100%
• Rotenone 69%
• Dopaminergic Neurons 55%
• Autophagy 50%
• Parkinson Disease 44%
• Synucleins 39%
• Oxidative Stress 38%
• Apoptosis 32%
• Inflammation 30%
• Antioxidants 14%
• Microglia 13%
• Lipid Peroxidation 12%
• Astrocytes 12%
• Monoterpenes 9%
• Phosphorylation 9%
• Pars Compacta 8%
• Beclin-1 8%
• Cytokines 8%
• TOR Serine-Threonine Kinases 7%
• Matrix Metalloproteinase 9 7%
• Interleukin-1 6%
• Intraperitoneal Injections 6%
• Rodentia 5%
• Reactive Oxygen Species 5%
• Interleukin-6 5%
• Anti-Inflammatory Agents 4%
• Homeostasis 4%
• Therapeutics 3%

Physics & Astronomy

• Parkinson disease 82%
• apoptosis 72%
• neurons 52%
• antioxidants 27%
• phosphorylation 18%
• impairment 15%
• lipids 12%
• etiology 10%
• activation 10%
• pathogenesis 10%
• homeostasis 9%
• rodents 9%
• activity (biology) 8%
• proteins 5%
• degradation 4%
• injection 4%
• modulation 4%
• dosage 4%
• products 4%
• oxygen 3%
• matrices 3%

Chemical Compounds

• Rotenone 73%
• Oxidative Stress 52%
• Antioxidant Agent 30%
• P62 21%
• Antiapoptotic 18%
• Lipid 18%
• Intraperitoneal 16%
• Monoterpene 15%
• Antiinflammatory 12%
• Reactive Oxygen Metabolite 12%
• Protective 10%
• Dose 10%
• Reduction 5%
• Protein 5%