Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19

Noura H. Abd Ellah, Sheryhan F. Gad, Khalid Muhammad, Gaber E Batiha, Helal F. Hetta

Research output: Contribution to journalReview articlepeer-review

72 Citations (Scopus)

Abstract

The COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.

Original languageEnglish
Pages (from-to)2085-2102
Number of pages18
JournalNanomedicine
Volume15
Issue number21
DOIs
Publication statusPublished - Sept 2020

Keywords

  • COVID-19
  • SARS-CoV-2
  • chloroquine
  • coronavirus
  • nanomedicine
  • remdesivir

ASJC Scopus subject areas

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • General Materials Science

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