Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19

Noura H. Abd Ellah; Sheryhan F. Gad; Khalid Muhammad; Gaber E Batiha; Helal F. Hetta

doi:10.2217/nnm-2020-0247

Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19

Noura H. Abd Ellah, Sheryhan F. Gad, Khalid Muhammad, Gaber E Batiha, Helal F. Hetta

Department of Biology

Research output: Contribution to journal › Review article › peer-review

72 Citations (Scopus)

Abstract

The COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.

Original language	English
Pages (from-to)	2085-2102
Number of pages	18
Journal	Nanomedicine
Volume	15
Issue number	21
DOIs	https://doi.org/10.2217/nnm-2020-0247
Publication status	Published - Sept 2020

Keywords

COVID-19
SARS-CoV-2
chloroquine
coronavirus
nanomedicine
remdesivir

ASJC Scopus subject areas

Bioengineering
Medicine (miscellaneous)
Biomedical Engineering
General Materials Science

Access to Document

10.2217/nnm-2020-0247

Cite this

@article{11ea1c798ea54dc3925972a2e55924dc,

title = "Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19",

abstract = "The COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.",

keywords = "COVID-19, SARS-CoV-2, chloroquine, coronavirus, nanomedicine, remdesivir",

author = "{Abd Ellah}, {Noura H.} and Gad, {Sheryhan F.} and Khalid Muhammad and {E Batiha}, Gaber and Hetta, {Helal F.}",

note = "Publisher Copyright: {\textcopyright} 2020 ",

year = "2020",

month = sep,

doi = "10.2217/nnm-2020-0247",

language = "English",

volume = "15",

pages = "2085--2102",

journal = "Nanomedicine",

issn = "1743-5889",

publisher = "Taylor and Francis Ltd.",

number = "21",

}

TY - JOUR

T1 - Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19

AU - Abd Ellah, Noura H.

AU - Gad, Sheryhan F.

AU - Muhammad, Khalid

AU - E Batiha, Gaber

AU - Hetta, Helal F.

PY - 2020/9

Y1 - 2020/9

N2 - The COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.

AB - The COVID-19 pandemic caused by the newly emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) puts the world in an unprecedented crisis, leaving behind huge human losses and deep socioeconomic damages. Due to the lack of specific treatment against SARS-CoV-2, effective vaccines and antiviral agents are urgently needed to properly restrain the COVID-19 pandemic. Repositioned drugs such as remdesivir have revealed a promising clinical efficacy against COVID-19. Interestingly, nanomedicine as a promising therapeutic approach could effectively help win the battle between coronaviruses (CoVs) and host cells. This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy.

KW - COVID-19

KW - SARS-CoV-2

KW - chloroquine

KW - coronavirus

KW - nanomedicine

KW - remdesivir

UR - http://www.scopus.com/inward/record.url?scp=85090509712&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85090509712&partnerID=8YFLogxK

U2 - 10.2217/nnm-2020-0247

DO - 10.2217/nnm-2020-0247

M3 - Review article

C2 - 32723142

AN - SCOPUS:85090509712

SN - 1743-5889

VL - 15

SP - 2085

EP - 2102

JO - Nanomedicine

JF - Nanomedicine

IS - 21

ER -

Nanomedicine as a promising approach for diagnosis, treatment and prophylaxis against COVID-19

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this