Neuroanatomical Findings in Unipolar Depression and the Role of the Hippocampus

Danilo Arnone

Research output: Chapter in Book/Report/Conference proceedingChapter


Depressive disorders are common conditions with a life prevalence of 15% in high-income countries (1) and significant economic implications for individuals and society. Major depressive disorders have negative repercussions on the overall quality of life of the people affected with an excess number of years lived with a disability (2). Although effective treatment is available, up to 65% of individuals do not fully respond or continue to experience residual symptoms, which contribute to significant disease burden (3). It is essential to improve our understanding of the neuroanatomy of depressive disorders and the functional implications to develop new targets for more efficacious treatments.

Original languageEnglish
Title of host publicationMood Disorders
Subtitle of host publicationBrain Imaging and Therapeutic Implications
PublisherCambridge University Press
Number of pages9
ISBN (Electronic)9781108623018
ISBN (Print)9781108427128
Publication statusPublished - Jan 1 2021

ASJC Scopus subject areas

  • General Medicine


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