TY - JOUR
T1 - Neuropsychological and activity of daily living script performance in patients with positive or negative schizophrenia
AU - Godbout, Lucie
AU - Limoges, Frédérique
AU - Allard, Isabelle
AU - Braun, Claude M.J.
AU - Stip, Emmanuel
PY - 2007
Y1 - 2007
N2 - Cognitive and psychiatric determinants of impairment of complex activities of daily living (ADLs) were investigated in 33 schizophrenic patients and 16 normal comparison subjects. The schizophrenic patients were cognitively impaired and were deficient in the ADL. However, the impairment of ADL could not be explained specifically by impairment of higher-order executive function or by negative symptoms: memory functions were more related to impairment of ADL and positive symptoms as much as the negative ones. Positive symptoms were significantly related to commissive errors in the ADL, whereas negative symptoms were nonsignificantly related to omissive errors. Negative symptoms were significantly more related to memory impairment than to impairment on measures of higher-order executive function (working memory). This investigation demonstrates that an ecologically oriented approach to test development and measurement of ADL is fruitful in understanding schizophrenia-especially if it is constrained by cognitive constructs compatible with the phenomenology of the disease.
AB - Cognitive and psychiatric determinants of impairment of complex activities of daily living (ADLs) were investigated in 33 schizophrenic patients and 16 normal comparison subjects. The schizophrenic patients were cognitively impaired and were deficient in the ADL. However, the impairment of ADL could not be explained specifically by impairment of higher-order executive function or by negative symptoms: memory functions were more related to impairment of ADL and positive symptoms as much as the negative ones. Positive symptoms were significantly related to commissive errors in the ADL, whereas negative symptoms were nonsignificantly related to omissive errors. Negative symptoms were significantly more related to memory impairment than to impairment on measures of higher-order executive function (working memory). This investigation demonstrates that an ecologically oriented approach to test development and measurement of ADL is fruitful in understanding schizophrenia-especially if it is constrained by cognitive constructs compatible with the phenomenology of the disease.
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U2 - 10.1016/j.comppsych.2007.01.003
DO - 10.1016/j.comppsych.2007.01.003
M3 - Article
C2 - 17445526
AN - SCOPUS:34147119507
SN - 0010-440X
VL - 48
SP - 293
EP - 302
JO - Comprehensive Psychiatry
JF - Comprehensive Psychiatry
IS - 3
ER -