New platinum and ruthenium complexes - The latest class of potential chemotherapeutic drugs - A review of recent developments in the field

Amr Amin; Michael A. Buratovich

doi:10.2174/138955709790361566

New platinum and ruthenium complexes - The latest class of potential chemotherapeutic drugs - A review of recent developments in the field

Amr Amin, Michael A. Buratovich

Research output: Contribution to journal › Short survey › peer-review

42 Citations (Scopus)

Abstract

New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.

Original language	English
Pages (from-to)	1489-1503
Number of pages	15
Journal	Mini-Reviews in Medicinal Chemistry
Volume	9
Issue number	13
DOIs	https://doi.org/10.2174/138955709790361566
Publication status	Published - Nov 2009

Keywords

Apoptosis
BBR3464
Cancer
Chemotherapeutics
Cisplatin
KP1019
Lipoplatin
NAMI-A
Picoplatin
RAPTA
Satraplatin

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Drug Discovery
Cancer Research

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abstract = "New Platinum and Ruthenium complexes display antitumour and antimetastatic potentials and lower host toxicities. This mini-review examines some the more recent developments in this field, and explores their interactions with biologically-relevant species. The article also refers to more recent work in the area of molybdenum and copper(II) chemistry.",

keywords = "Apoptosis, BBR3464, Cancer, Chemotherapeutics, Cisplatin, KP1019, Lipoplatin, NAMI-A, Picoplatin, RAPTA, Satraplatin",

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KW - Apoptosis

KW - BBR3464

KW - Cancer

KW - Chemotherapeutics

KW - Cisplatin

KW - KP1019

KW - Lipoplatin

KW - NAMI-A

KW - Picoplatin

KW - RAPTA

KW - Satraplatin

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New platinum and ruthenium complexes - The latest class of potential chemotherapeutic drugs - A review of recent developments in the field

Abstract

Keywords

ASJC Scopus subject areas

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