Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

Medicine & Life Sciences

• Anticonvulsants 56%
• Brain 8%
• Computer Simulation 8%
• Electroshock 33%
• Epilepsy 7%
• Extremities 6%
• Histamine H3 Antagonists 100%
• Histamine H3 Receptors 12%
• In Vitro Techniques 7%
• Ligands 42%
• Pentylenetetrazole 21%
• Pharmaceutical Preparations 3%
• Phenytoin 9%
• Pyrilamine 23%
• Reverse-Phase Chromatography 10%
• Seizures 46%
• Strychnine 11%
• Synaptic Transmission 7%
• Thin Layer Chromatography 10%
• zolantidine 32%

Chemical Compounds

• Adjuvant 10%
• Antagonist 15%
• Anticonvulsant 9%
• Drug 4%
• Histamine 9%
• Histamine H3 Receptor Antagonist 97%
• Ligand 26%
• Lipophilicity 8%
• Pharmacological Metabolism 13%
• Phenytoin 11%
• Protective 28%
• Reduction 3%
• Reversed Phase Thin Layer Chromatography 12%
• Strychnine 12%