Non-invasive estimation of hemoglobin, bilirubin and oxygen saturation of neonates simultaneously using whole optical spectrum analysis at point of care

Amrita Banerjee, Neha Bhattacharyya, Ria Ghosh, Soumendra Singh, Aniruddha Adhikari, Susmita Mondal, Lopamudra Roy, Annie Bajaj, Nilanjana Ghosh, Aman Bhushan, Mahasweta Goswami, Ahmed S.A. Ahmed, Ziad Moussa, Pulak Mondal, Subhadipta Mukhopadhyay, Debasis Bhattacharyya, Arpita Chattopadhyay, Saleh A. Ahmed, Asim Kumar Mallick, Samir Kumar Pal

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The study was aimed to evaluate the performance of a newly developed spectroscopy-based non-invasive and noncontact device (SAMIRA) for the simultaneous measurement of hemoglobin, bilirubin and oxygen saturation as an alternative to the invasive biochemical method of blood sampling. The accuracy of the device was assessed in 4318 neonates having incidences of either anemia, jaundice, or hypoxia. Transcutaneous bilirubin, hemoglobin and blood saturation values were obtained by the newly developed instrument which was corroborated with the biochemical blood tests by expert clinicians. The instrument is trained using Artificial Neural Network Analysis to increase the acceptability of the data. The artificial intelligence incorporated within the instrument determines the disease condition of the neonate. The Pearson’s correlation coefficient, r was found to be 0.987 for hemoglobin estimation and 0.988 for bilirubin and blood gas saturation respectively. The bias and the limits of agreement for the measurement of all the three parameters were within the clinically acceptance limit.

Original languageEnglish
Article number2370
JournalScientific reports
Volume13
Issue number1
DOIs
Publication statusPublished - Dec 2023

ASJC Scopus subject areas

  • General

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